Hyponatremia may lead to hepatic encephalopathy

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Hepatic encephalopathy

Hepatic encephalopathy (HE) is a reversible syndrome of impaired brain function occurring in patients with advanced liver diseases. The precise pathophysiology of HE is still under discussion; the leading hypothesis focus on the role of neurotoxins, impaired neurotransmission due to metabolic changes in liver failure, changes in brain energy metabolism, systemic inflammatory response and altera...

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Correlation of hyponatremia with hepatic encephalopathy and severity of liver disease.

OBJECTIVE To assess the frequency of low serum sodium levels and to correlate it with the severity of liver disease and hepatic encephalopathy (HE) in patients coming to the tertiary care hospital. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY Shifa International Hospital, Islamabad, from January 2011 to January 2012. METHODOLOGY A total of 202 patients with hepatic enceph...

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Hepatic Encephalopathy

The liver is the most important organ for the well-functioning of other organs because of its vital role in nutrition, metabolism and secretion. Any disturbance in normal homeostasis of liver as it happens in acute liver failure (ALF) and chronic liver disease (cirrhosis) will lead to extra hepatic manifestations of liver disease, among them one is encephalopathy. And this encephalopathy caused...

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ژورنال

عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology

سال: 2009

ISSN: 1759-5045,1759-5053

DOI: 10.1038/nrgastro.2009.118